Programme overview

Programme

Programme

Overview by day

Monday

Time Monday Trainer
9:00-10:00
10:00-11:00 Registration Silke Kniffert & Celine Heinl
11:00-12:00 Introduction to Barcamp Ulf Toelch
——– ————- ——-
12:00-13:00 Break Break
——– ————- ——-
13:00-17:00 Barcamp Ulf, Celine, Mex, Anja, Evgeny
18:00-21:00 Welcome Reception

Tuesday

Time Tuesday Trainer
9:00-10:00 Reproducibility Intro Laura Fortunato
10:00-11:00 Research Ethics Jonathan Kimmelmann
11:00-12:00 Waste and Value Ulrich Dirnagl
——– ————- ——-
12:00-13:00 Break Break
——– ————- ——-
13:00-17:00 1. Virtue Ethics Marlene Stoll
13:00-17:00 2. REDUCE Lars Lewejohann
13:00-17:00 3. Intro to R Meggie Danziger, Anja Collazo
13:00-17:00 4. Systematic Review Alexandra Bannach-Brown
13:00-17:00 5. REPLACE, Lab Visit Michael Oelschlaeger, Tanja Burgdorf and Kostja Renko & Katja Hönzke

Wednesday

Time Monday Trainer
9:00-10:00 Research Data Management Nina Weisweiler
10:00-11:00 Preregistration Celine Heinl
11:00-12:00 Replication Ulf Toelch
——– ————- ——-
12:00-13:00 Break Break
——– ————- ——-
13:00-17:00 1. Visualization Vladislav Nachev
13:00-17:00 2. Preregistration of Animal Studies Julia Menon
13:00-17:00 3. Preregistration Malika Ihle
13:00-17:00 4. Publish your Protocol Rene Bernard
18:00-19:00 Keynote Lecture Replication Tim Errington
19:00-21:30 Social event

Thursday

Time Monday Trainer
9:00-10:00 Meta Research Tracey Weissgerber
10:00-11:00 Screening Tools Anita Bandrowski
11:00-12:00 Privacy Preserving Data Sharing Fabian Prasser & Thierry Meurers
——– ————- ——-
12:00-13:00 Break Break
——– ————- ——-
13:00-17:00 1. Reproducible Analysis Aaron Peikert
13:00-17:00 2. REFINE Kai Diederich
13:00-17:00 3. Science Communication Stefanie Seltmann & Katharina Kalhoff
13:00-17:00 4. GIT, GIT Hub Malika Ihle
18:00-21:00 Speaker’s Dinner

Friday

Time Monday Trainer
9:00-10:00 Diversity Cassandra Gould van Praag
10:00-11:00 Open Publishing Jenny Delasalle
11:00-12:00 Transparency Initiative & Student Journal Berlin Exchange Medicine Anne-Marike Schiffer & Clara Weber, Raphael Leuner
——– ————- ——-
12:00-13:00 Break Break
——– ————- ——-
13:00-17:00 Panel discussion Gilbert Schönfelder, Anne-Marike Schiffer, Cassandra Gould van Praag

Overview of all lecturers & trainers

academic_title first_name surname
M. Sc. Aaron Peikert
Specialist and BIH Visiting Professor Anita Bandrowski
Dr Cassandra Gould van Praag
Dr. Céline Heinl
Prof. Dr. Fabian Prasser
Professor Jonathan Kimmelman
MSc Julia Menon
Dr. Kai Diederich
Prof. Dr. Lars Lewejohann
Associate Professor of Evolutionary Anthropology Laura Fortunato
Dr Malika Ihle
Dr. Marlene Stoll
Dr. Michael Oelgeschläger
Information Science (M. A.) Nina Weisweiler
Dr. René Bernard
Dr. Stefanie Seltmann
Dr Tanja Burgdorf
Senior Director of Research Timothy Errington
Dr. Vladislav Nachev

Speakers information per day

Lecturers Tuesday

1. Laura Fortunato

Laura Fortunato

Laura Fortunato

speakers_info
Laura Fortunato is Associate Professor of Evolutionary Anthropology at the University of Oxford, Tutorial Fellow in Evolutionary Anthropology at Magdalen College, Oxford, and an External Professor at the Santa Fe Institute. In 2016 she founded Reproducible Research Oxford (RROx), and in 2019 she co-founded (with three others) the UK Reproducibility Network (UKRN). Her interests in this area focus on the provision of training, on effective computing for reproducibility, and on the use of free and open source software.
affiliation
University of Oxford

2. Jonathan Kimmelmann

Jonathan Kimmelmann

Jonathan Kimmelmann

speakers_info
Jonathan Kimmelman, PhD, is James McGill Professor of Biomedical Ethics at McGill University, and directs the Biomedical Ethics Unit as well as his own research group, STREAM (Studies in Translation, Ethics and Medicine). Kimmelman’s research centers on ethical, policy, and scientific dimensions of clinical development. Kimmelman received the Maud Menten New Investigator Prize (2006), a CIHR New Investigator Award (2008), a Humboldt Bessel Award (2014), and was elected a Hastings Center Fellow (2018). He has sat on various advisory bodies within the U.S. NHLBI and NIAID, served for four tours of duty on U.S. National Academies of Medicine committees, and chaired the International Society of Stem Cell Research Guidelines for Stem Cell Research and Clinical Translation revision task force 2015-16. His research has been covered in major media outlets, including NPR’s All Things Considered, STATNews, and Nature. Kimmelman is deputy editor at Clinical Trials, and associate editor at Cell Med.
affiliation
Dept. of Equity, Ethics and Policy, McGill University

3. Ulrich Dirnagl

Ulrich Dirnagl

Ulrich Dirnagl

speaker information
At the Charité Universitätsmedizin Berlin Ulrich Dirnagl is Professor for Clinical Neurosciences and served as Director of the Department of Experimental Neurology until 4/2022. Since 2017 he is the founding director of the QUEST Center for Transforming Biomedical Research at the Berlin Institute of Health. QUEST aims at overcoming the roadblocks in translational medicine by increasing the value and impact of biomedical research through maximizing the quality, reproducibility, generalizability, and validity of research.
In preclinical as well as in clinical studies Ulrich Dirnagl’s research has revealed pathobiology which impact on the outcome after a stroke. These include deleterious as well as endogenous protective mechanisms, as interactions of the brain with other systems of the body after it has been injured. Several of these mechanism can be therapeutically targeted, clinical trials are under way. In addition, through meta-research he was able to identify opportunities for improving research practice and to obtain evidence for the impact of interventions targeted to increase the value of biomedical research.
affiliation
Berlin Institute of Health (BIH) at Charité, BIH QUEST Center for Responsible Research

Lecturers Wednesday

1. Nina Weisweiler

Nina Weisweiler

Nina Weisweiler

speakers_info
After completing her Master’s degree in Information Science at Humboldt-Universität zu Berlin in 2019, Nina started her involvement in open access and open science with a position as Discovery & Project Manager at Knowledge Unlatched. Since 2020, she has been working in the Helmholtz Open Science Office and contributes to its mission “Enabling Open Science practices in Helmholtz!”. Among various other activities, she is responsible for outreach and community management in the re3data COREF project, which is dedicated to improving and further professionalizing re3data – the Registry of Research Data Repositories.
affiliation
Helmholtz Association, Helmholtz Open Science Office

2. Celine Heinl

Celine Heinl

Celine Heinl

speakers_info
Céline Heinl studied Biology at the Free University of Berlin and the University Paul Sabatier in Toulouse. She obtained her PhD in Neuroscience from the Medical University of Vienna and pursued her research on neuronal processing of pain as a postdoc at Heidelberg University. In 2017 she joined the German Centre for the Protection of Laboratory Animals (Bf3R) at the Federal Institute for Risk Assessment (BfR) in Berlin to help develop the animalstudyregistry.org, a preregistration platform for animal studies that was launched in 2019.
affiliation
German Centre for the Protection of Laboratory Animals (Bf3R) at the Federal Institute for Risk Assessment (BfR)

3. Ulf Toelch

Ulf Toelch

Ulf Toelch

speaker information
Ulf did his PhD in Behvioural Biology with an emphasis on animal cognition. He then turned into cultural evolution and later cognitive neuroscience of social learning in humans. With a passion for teaching, he developed several teaching formats for open and responsible research practices. He now serves as head of a research group at the BIH QUEST Center for Responsible Research looking into reproducibility in preclinical research.
affiliation
Berlin Institute of Health (BIH) at Charité, BIH QUEST Center for Responsible Research

Lecturers Thursday

1. Tracey Weissgerber

Tracey Weissgerber

Tracey Weissgerber

speaker information
Tracey Weissgerber leads the Meta-research and Automated Screening group at QUEST. Her team focuses on improving data visualization, transparency and methodological reporting in scientific publications. Research from her team has prompted many journals to implement new policies asking authors to replace bar graphs of continuous data with more informative graphics. She also organizes ScreenIT, a group of biologists and software developers that have designed tools to detect common problems or beneficial practices in preprints and scientific publications. The group has used these tools to post public reports on more than 25,000 COVID-19 preprints.
affiliation
Berlin Institute of Health (BIH) at Charité, BIH QUEST Center for Responsible Research

2. Anita Bandrowski

Anita Bandrowski

Anita Bandrowski

speakers_info
Dr Bandrowski trained as a bench neurophysiologist, working to elucidate physiological mechanisms of learning and epilepsy. However, soon after postdoc, Dr. Bandrowski began to work in data, starting with the annotation of the human genome for Celera Inc. Dr. Bandrowski moved to neuroinformatics with the award of the Neuroscience Information Framework by the NIH’s Blueprint for Neuroscience. The goal of this project was to create a comprehensive list of databases for neuroscience and to federate search across as many of these databases as possible. The framework grew to the most comprehensive search system for neuroscience data on the web. This broad overview of the data landscape highlighted the need to align and structure data and dearth of reagent information, especially how reagents and tools are cited in the scientific literature.

The process of data curation is the structuring and aligning of data to meet the needs of some downstream group, mechanism, or database. Dr. Bandrowski’s work was initially to structure data into a particular format, to meet the needs of the PANTHER database, however, her role moved to creating data structures that are accessible to multiple systems, or FAIR (findable, accessible, interoperable, and reusable); leading interdisciplinary teams to create community standards, and structuring data into formats that are accessible to artificial intelligence systems.

To address reagent underreporting issues, Dr. Bandrowski serves as the lead for the Research Resource Identification, RRID, Initiative, a group dedicated to transforming scholarly communication, which has recently become a non-profit organization. RRIDs are unique identifiers for Key Biological Resources, aggregated by our group from community databases and requested from authors in participating journals. |

affiliation
Dept of Neuroscience, UCSD and
BIH Visiting Professor, funded by Stiftung Charité

3. Fabian Prasser

Fabian Prasser

Fabian Prasser

speakers_info
Fabian Prasser is Professor of Medical Informatics at Charité – Universitätsmedizin Berlin and the Berlin Institute of Health where he heads the Medical Informatics Group. His research interests include the design of data sharing infrastructures, big data architectures for translational medical research and related data protection and information security challenges.
affiliation
Berlin Institute of Health, Medical Informatics

4. Thierry Meurers

Thierry Meurers

Thierry Meurers

speaker information
Thierry Meurers studied computer science at the Free University of Berlin and did his master’s degree while working for a medical device company. Since 2020 he is a PhD student in the BIH Medical Informatics Group and Charité’s Health Data Sciences PhD program. His research focuses on privacy-enhancing technologies and the question how medical data can safely be shared for scientific purposes without impeding the privacy of individuals. A particular focus is on the topic of data anonymization and how it can be put into practice.
affiliation
Berlin Institute of Health at Charité – Universitätsmedizin Berlin

5. Timothy Errington

Timothy Errington

Timothy Errington

speakers_info
Tim Errington is Senior Director of Research at the Center for Open Science (COS) that aims to increase openness, integrity, and reproducibility of scientific research. In that position he conducts and collaborates with researchers and stakeholders across scientific disciplines and organizations on metascience projects aimed to understand the current research process and evaluate initiatives designed to increase reproducibility and openness of scientific research. Such projects include large scale reproducibility projects, such as the Reproducibility Project: Cancer Biology and the DARPA supported Systematizing Confidence in Open Research and Evidence (SCORE) (doi.org/10.31235/osf.io/46mnb) and evaluation projects of new initiatives, such as open science badges (doi.org/10.1371/journal.pbio.1002456) and Registered Reports (doi.org/10.1038/s41562-021-01142-4).
affiliation
Center for Open Science

Lecturers Friday

1. Cassandra Gould van Praag

Cassandra Gould van Praag

Cassandra Gould van Praag

speakers_info
The main focus of my role is to generate opportunities for the research community to use, actively participate in and contribute to the open science infrastructure of the Wellcome Centre for Integrative Neuroimaging (WIN), the MRC Brain Network Dynamics Unit (BNDU) and the NIHR Oxford Health Biomedical Research Centre (BRC). I am also responsible for developing policy and training to support infrastructure uptake and researcher engagement. Prior to this role I undertook postdoctoral research in Psychiatry (2014-2020, University of Oxford and University of Sussex, UK). I completed my PhD in Informatics (2014, University of Oxford), have an MSc in Cognitive Neuropsychology (2008, University College London, UK) and a BSc in Biological Sciences (2005, University of Brighton, UK). I am a keen contributor to both open science and professional academic community manager spaces.
affiliation
Wellcome Centre for Integrative Neuroimaging, University of Oxford

2. Jenny Delasalle

Jenny Delasalle

Jenny Delasalle

speaker information
Jenny Delasalle is a professional librarian and has over twenty years of experience in supporting researchers in the UK and Germany. Jenny joined the Open Access (OA) Team of the Charité Medical Library in January 2018, and began leading the team in 2020 when she was also appointed OA-Beauftragte to the Charité, or OA-Envoy. Jenny and her team run one of Germany’s largest publication funds, organise participation in relevant publisher agreements and the team posts hundreds of publications to the Charité’s institutional repository each year. Prior to joining the Charité, Jenny worked as a freelancer for universities, publishers and software vendors and before that she worked at the University of Warwick, where she was the founding manager of their institutional repository and set up one of the first open access publication funds in England.
affiliation
Charité - Universitätsmedizin Berlin

3. Anne Marike Schiffer

Marike Schiffer

Marike Schiffer

affiliation
Communications Psychology Springer Nature

3. Clara Weber

Clara Weber

Clara Weber

speaker information
Clara Weber studies medicine and medical computer science at Luebeck University, and works in neurodevelopment research for Yale and McGill University. She is Open Science Coordinator at Berlin Exchange Medicine.
affiliation
Luebeck university, Yale and McGill University

3. Raphael Leuner

Raphael Leuner

Raphael Leuner

speaker information
Raphael Leuner is a data science student at Freie Universitaet Berlin. He is editor for data and statistics at Berlin Exchange Medicine as well as integral part of the Open Science team at BEM as well as our technical infrastructure, and intiated our Open Science policy.
affiliation
Freie Universitaet, Berlin

6. Gilbert Schoenfelder

Gilbert Schönfelder

Gilbert Schönfelder

speaker information
Professor Dr. Gilbert Schönfelder is a physician, university professor at the Institute for Clinical Pharmacology and Toxicology at the Charité and heads the department of “Experimental Toxicology and Toxicology and ZEBET” and the German Center for the Protection of Laboratory Animals (Bf3R). Schönfelder’s research focuses on the the field of experimental toxicology, the further development of alternative methods to animal experimentation, as well as reproductive and developmental toxicology.
He studied human medicine at the at the Freie Universität of Berlin, and in 2003 became a junior professor at the Charité, moved to the the University of Würzburg in 2007 and returned to the Charité in 2010. Since 2012, Schönfelder has been at the BfR.
affiliation
German Federal Institute for Risk Assessment (BfR)

Trainers information per day

Trainers Monday

1. Ulf Toelch

Ulf Toelch

Ulf Toelch

speaker information
Ulf did his PhD in Behvioural Biology with an emphasis on animal cognition. He then turned into cultural evolution and later cognitive neuroscience of social learning in humans. With a passion for teaching, he developed several teaching formats for open and responsible research practices. He now serves as head of a research group at the BIH QUEST Center for Responsible Research looking into reproducibility in preclinical research.
affiliation
Berlin Institute of Health (BIH) at Charité, BIH QUEST Center for Responsible Research

2. Celine Heinl

Celine Heinl

Celine Heinl

speakers_info
Céline Heinl studied Biology at the Free University of Berlin and the University Paul Sabatier in Toulouse. She obtained her PhD in Neuroscience from the Medical University of Vienna and pursued her research on neuronal processing of pain as a postdoc at Heidelberg University. In 2017 she joined the German Centre for the Protection of Laboratory Animals (Bf3R) at the Federal Institute for Risk Assessment (BfR) in Berlin to help develop the animalstudyregistry.org, a preregistration platform for animal studies that was launched in 2019.
affiliation
German Centre for the Protection of Laboratory Animals (Bf3R) at the Federal Institute for Risk Assessment (BfR)

3. Evgeny Bobrov

Evgeny Bobrov

Evgeny Bobrov

speaker information
Dr. Evgeny Bobrov is Open Data and Research Data Management (FDM) Project Leader at the QUEST Center of the Berlin Institute for Health Research at Charité. He coordinates institutional activities in the field of FDM and supports researchers by providing advice and training on FDM topics, often with a focus on personal data. In addition, he is involved in projects that further develop FDM at the level of the Berlin University Alliance and investigate the openness and reusability of research data at Charité and beyond.
affiliation
Berlin Institute of Health (BIH) at Charité, BIH QUEST Center for Responsible Research

4. Meggie Danziger

Meggie Danziger

Meggie Danziger

speaker information
Meggie holds a Master of Science in Cognitive Neuroscience and switched to Meta-Research for her doctoral studies. In her PhD projects she is exploring methods to increase the reliability and reproducibility of preclinical animal research.
affiliation
Berlin Institute of Health (BIH) at Charité, BIH QUEST Center for Responsible Research

5. Anja Collazo

Anja Collazo

Anja Collazo

speaker information
Anja joined QUEST as a PhD student within the Charité Health Data Science program. She is part of research projects aiming at attaining higher validity and reliability of preclinical confirmatory studies to help decision-making towards clinical translation. Her focus is on conceptual approaches to sample size calculation, definitions of replicability and theory building through causal inference methods in laboratory animal sciences.
affiliation
Berlin Institute of Health (BIH) at Charité, BIH QUEST Center for Responsible Research

Trainers Tuesday

1. Marlene Stoll

Marlene Stoll

Marlene Stoll

speakers_info
After my studies of psychology, I did my doctorate in a interdisciplinary project about the independence of research at the University Medical Center Mainz, Germany. My dissertation topic was the unintended consequences of conflict of interest disclosure in medicine. Since 2020, I have been working at the Leibniz Institute for Psychology (ZPID) in Trier and the Leibniz Institute for Resilience Research (LIR) in Mainz in the project “PLan Psy”, in which we develop evidence-based guidelines for psychological plain language summaries, with a special focus on the lay friendly communication of evidence quality and risk of bias. I am also a research integrity trainer and coach.
affiliation
Leibniz Institute for Psychology (ZPID), Trier, Germany
Leibniz Institute for Resilience Research (LIR), Mainz, Germany

2. Lars Lewejohann

Lars Lewejohann

Lars Lewejohann

speakers_info
Lars Lewejohann (*1970) studied Biology and Philosophy at the University of Muenster. Already in his diploma thesis (1999) he dealt with the evaluation of housing conditions of laboratory mice from an animal’s point of view using preference tests. In his PhD-project “Behavioral Phenotyping of Mice: Methods, Evaluation, and Appliance” a test battery for murine models used in biomedical research was developed. He has held interim professorships for Behavioral Biology at the Universities of Osnabrueck and Goettingen. Since April 2017 he is a professor for animal welfare and refinement at the Freie Universität Berlin and the Head of Unit “Laboratory Animal Science” at the German Center for the Protection of Laboratory Animals (Bf3R) at the Federal Institute for Risk Assessment (BfR), Berlin. In the Lewejohann lab new concepts of social and environmental enrichment in order to counteract animal boredom in laboratory animals are developed. In addition, individual differences, the interplay of cognition and emotion, and the animals’ point of view with regard to better housing conditions and experimental designs are among his current research topics.
affiliation
Laboratory Animal Science, Federal Institute for Risk Assessment (BfR)
Institute of Animal Welfare, Animal Behavior and Laboratory Animal Science, Freie Universität Berlin

3. Anja Collazo

Anja Collazo

Anja Collazo

speaker information
Anja joined QUEST as a PhD student within the Charité Health Data Science program. She is part of research projects aiming at attaining higher validity and reliability of preclinical confirmatory studies to help decision-making towards clinical translation. Her focus is on conceptual approaches to sample size calculation, definitions of replicability and theory building through causal inference methods in laboratory animal sciences.
affiliation
Berlin Institute of Health (BIH) at Charité, BIH QUEST Center for Responsible Research

4. Meggie Danziger

Meggie Danziger

Meggie Danziger

speaker information
Meggie holds a Master of Science in Cognitive Neuroscience and switched to Meta-Research for her doctoral studies. In her PhD projects she is exploring methods to increase the reliability and reproducibility of preclinical animal research.
affiliation
Berlin Institute of Health (BIH) at Charité, BIH QUEST Center for Responsible Research

5. Alex Bannach-Brown

Alexandra Bannach-Brown

Alexandra Bannach-Brown

speaker information
Alex is a preclinical systematic review & meta-analysis methodologist at QUEST Center, Berlin Institute of Health @ Charité Universitaetsmedizin Berlin. She works to grow evidence synthesis in biomedicine through education, infrastructure and building communities. She has expertise in automating evidence synthesis methodology, meta-research of preclinical animal models in neuropsychiatry, working in an open science and open data framework to promote research transparency and integrity. CAMARADES Berlin https://www.camarades.de/
affiliation
Berlin Institute of Health (BIH) at Charité, BIH QUEST Center for Responsible Research

6. Michael Oelgeschlaeger

Michael Oelgeschlaeger

Michael Oelgeschlaeger

speakers_info
Dr Michael Oelgeschläger studied biology in Hannover (Germany) and Boston (USA). After completed his PhD thesis in molecular biology he worked as a
Postdoc work in the laboratories of Prof. A. Nordheim (Hannover) and Prof. E.M. De Robertis (UCLA/ HHMI, USA) on transcriptional regulation and mechanisms regulating early embryonic patterning processes. He continoued this work as an independent group leader at the Max-Planck institute for immunology (Freiburg, Germany) and habilitated in the field of developmental biology. He joined the BfR in 2002, and focused on the development and implementation of novel in vitro test methods as well as supporting various OECD expert groups. Since 2014 he is the German national coordinator of the OECD test guideline program (human health) and since 2016 head of the Unit “Strategies for Toxicological Assessments”. His current research addresses the optimization of test methods considering circadian rhythm and the development of new HT-HC compatible cell based and invertebrate (C. elegans) testing approaches with a focus on the role of nuclear receptors in carcinogenicity and metabolic disease.
affiliation
German Federal Institute for Risk Assessment

7. Tanja Burgdorf

Speaker information
Dr. Tanja Burgdorf (f) studied chemistry in Braunschweig/Germany and Bordeaux/France and obtained her PhD in microbiology. Afterwards she worked as a post doc and assistant lecturer at the Humboldt University (Berlin, Germany). She joined the BfR research coordination as a senior scientist in 2006. Her main responsibilities were acquisition of third-party funds, project management and administration, international collaboration, evaluation and presentation of research activities, and strategic research planning. Since 2014 she is working in the Unit “Strategies for Toxicological Assessments” and is head of the BfR working group for the (further) development of test guidelines. As a member of the WPHA, the EAGMST, and the IATA case studies project, she is involved in the OECD work on testing strategies test guidelines. In the EU funded project RiskHunt3R, she is working on assessing readiness levels of new methods regarding their transfer into regulation.
affiliation
German Federal Institute for Risk Assessment

8. Kostja Renko

Kostja Renko

Kostja Renko

speaker information
affiliation
German Federal Institute for Risk Assessment

9. Katja Hönzke

Katja Hoenzka

Katja Hoenzka

speaker information
Since 10/2014 Principal Investigator, Charité- Universitätsmedizin Berlin, Medical Department Division of Infectiology and Pneumology, Berlin
01/2012 - 09/2014 Post-doctoral fellow, OncoRay- National Center for Radiation Research in Oncology, Dresden

01/2011 - 12/2011 Post-doctoral fellow, Tufts Medical Center, Division of Newborn Medicine, Boston, USA

07/2009 - 12/2010 Post-doctoral fellow, Hannover Medical School, Department of Pediatrics, Hannover
10/2005 - 06/2009 PhD Program ” Molecular Medicine”, Biomedical Research School, Department of Pediatrics, Hannover
09/2000 - 09/2005 Biotechnology studies, University of Applied Science, Senftenberg
affiliation
Charité - Universitätsmedizin Berlin Department of Internal Medicin/ Infectious Disease and Pulmonary Medicine

Trainers Wednesday

1. Vladislav Nachev

Vladislav Nachev

Vladislav Nachev

speaker information
Vladislav is a research biologist by training, who is passionate about open science, data, and education. He has recently joined the QUEST Center for Responsible Research as a data scientist. Previously, Vladislav has taught data analysis of animal behavior for over ten years at the Humboldt-Universität zu Berlin. He obtained his Doctorate degree also at the Humboldt-Universität zu Berlin, where he studied the foraging behavior of nectar-feeding bats.
affiliation
BIH QUEST

2. Julia Menon

Julia Menon

Julia Menon

speakers_info
Julia Menon is the Daily Director of Preclinicaltrials.eu. She is from background a biomedical biologist but has evolved in her career through meta-research, particularly preclinical systematic reviews and qualitative studies. She is a research fellow at The Netherlands Organisation for Health Research and Development, where she conducts research on tools and methods to improve animal research’s transparency and robustness. Her current focus lies on preregistration of animal studies and how it may improve study quality and accessibility. She is also part of the SyRCLE’s network, is an administrator for the platform PROSPERO & is a section editor for Laboratory Animals.
affiliation
1) Preclinicaltrials.eu, Netherlands Heart Institute, Utrecht, the Netherlands
2) Netherlands Organisation for Health Research and Development (ZonMw), the Hague, the Netherlands

3. Malika Ihle

Malika Ihle

Malika Ihle

speakers_info
I am the coordinator of the LMU Open Science Center since May 2022. The remits of this role include developing an open research curriculum, organise and deliver events and workshops, coordinate grassroots initiatives, support meta-research collaborations, and network with local, national, and international stakeholders to inform the design of incentives and policies. Prior to this, I have been in a similar role for 2.5 years at the University of Oxford, supporting Reproducible Research Oxford (RROx) in developing a comprehensive approach to open scholarship and reproducible research that extends across all disciplines, using both bottom-up and top-down strategies. I hold a PhD in Biology, and I am a founding member of the Society for Open, Reliable, and Transparent Ecology and Evolutionary biology (SORTEE).
affiliation
LMU Munich

4. Rene Bernard

Rene Bernard

Rene Bernard

speakers_info
I am an internationally trained pharmacist, pharmacologist, and neuroscientist with a keen interest in research quality, reporting transparency, research data management, and all things related to open science. I am also the co-developer of two preclinical quality management systems. More information and all publications are accessible via my ORCID profile - http://orcid.org/0000-0003-3265-2372
affiliation
NeuroCure Cluster of Excellence - Charité Universitätsmedizin
QUEST Center of the BIH

Trainers Thursday

1. Aaron Peikert

Aaron Peikert

Aaron Peikert

speakers_info
Aaron Peikert earned his Bachelor’s and Master’s degrees in Psychology at Humboldt University in Berlin (HU). One of the first things he learned in Introduction to Research Methods was that about half of what he would be taught during his studies was wrong: Ever since, he has been trying to figure out which half that is. In this quest, he initially focused on statistical methods and psychometrics as a student assistant at HU’s Department of Diagnostics. He broadened his view and focused on Open Science practices in general when he joined the “Formal Methods Group in Lifespan Psychology” at the Max Plank Institute for Human Development (MPIB) as a student assistant, where he now continues his quest as a PhD student. At MPIB, his research focuses on computational reproducibility and philosophy of open science. To achieve computational reproducibility (getting the same results from the same data), he integrated best practices from software engineering and research. His goal is to convince researchers that software engineering tools are necessary for data analytic research, and to increase the usability of these tools. Along the way, he is actively developing the software StructuralEquationModels.jl and exploring the utility of regularized structural equation models for theory development and random effects approaches for machine learning algorithms.
affiliation
Max Planck Institute for Human Development

2. Kai Diederich

Kai Diederich

Kai Diederich

speakers_info
I am a neurobiologist by profession and by passion. I studied biology in Osnabrück and Bremen, majoring in neurobiology and psychology. After my PhD at the University Hospital Münster, I co-led a research group for experimental stroke research for ten years. Since 2017, I have been working as a scientist at the German Center for the Protection of Laboratory Animals on strategies to assess and improve the welfare of laboratory animals and to improve the reproducibility and transferability of animal experimental research.
affiliation
German Federal Institute for Risk Assessment

German Centre for the Protection of Laboratory Animals Unit Laboratory Animal Sciences |

3. Stefanie Seltmann

Stefanie Seltmann

Stefanie Seltmann

spaeker information
Dr. Stefanie Seltmann studied biology at Heidelberg University and obtained her PhD at the German Cancer Research Center (DKFZ) in molecular biology. She has over 20 years of experience in science communication. She has worked as a journalist and reporter for the public radio (SWR), was the Head of Press and Public Relations at the DKFZ and Director for external communications at Pfizer Germany. Since 2018, she has been working as Head of Communications at the Berlin Institute of Health at Charité (BIH).
affiliation
Berlin Institute of Health at Charité (BIH)

4. Katharina Kalhoff

Katharina Kalhoff

Katharina Kalhoff

speaker information
With Stefanie Seltmann is her young colleague Katharina Kalhoff, who holds a master’s degree in journalism and has worked for various media and television in Germany and France. Katharina is online-editor in BIH´s communications team.
affiliation
Berlin Institute of Health at Charité (BIH)

5. Malika Ihle

Malika Ihle

Malika Ihle

speakers_info
I am the coordinator of the LMU Open Science Center since May 2022. The remits of this role include developing an open research curriculum, organise and deliver events and workshops, coordinate grassroots initiatives, support meta-research collaborations, and network with local, national, and international stakeholders to inform the design of incentives and policies. Prior to this, I have been in a similar role for 2.5 years at the University of Oxford, supporting Reproducible Research Oxford (RROx) in developing a comprehensive approach to open scholarship and reproducible research that extends across all disciplines, using both bottom-up and top-down strategies. I hold a PhD in Biology, and I am a founding member of the Society for Open, Reliable, and Transparent Ecology and Evolutionary biology (SORTEE).
affiliation
LMU Munich

Abstracts of the lectures

Tuesday

1. Setting the scene: open research, reproducibility, and research culture by Laura Fortunato

I will briefly outline key concepts at the interface between open research and research culture, including for example definitions of reproducibility and how they apply across fields. I will then introduce Reproducible Research Oxford and the UK Reproducibility Network as examples of researcher-led efforts that aim to contribute practical solutions at this interface.

2. Research ethics by Jonathan Kimmelmann

Ethical conduct of research and current ethical problems.

3. Waste and Value by Ulrich Dirnagl

Wednesday

1. Best Practices for Open Science in Data Sharing and Research Data Management by Nina Weisweiler

Digital transformation and open science are fundamentally changing the way research data is handled and reused. In many scientific disciplines, research data publications have evolved from a by-product to a decisive factor for researchers’ careers. Instead of making data available only for the sake of form or on request, there is a strong trend towards the independent and prominent publication of research data in open form.
The talk will take into account these influential developments and discuss data publishing as a central activity within the open science paradigm. Within this framework, published datasets should become FAIR – findable, accessible, interoperable and reusable. Research data repositories are critical to facilitating the publication of research data in accordance with these criteria. The presentation will provide an introduction to such digital infrastructures, and will also focus on re3data – the Registry of Research Data Repositories, which assists researchers in selecting appropriate repositories for storing and searching research data. Publishing citable research datasets in reliable repositories with proper attribution and a persistent identifier (e.g., DOI) not only improves accessibility and reproducibility, but also increases visibility and rewards for the data creators.

2. Preregistration by Celine Heinl

Preregistration is a proven tool to increase research quality and reporting. By registering a study plan before starting experiments in a public registry or submitting it to a journal, questionable research practices and publication bias can effectively be addressed. Preregistration is already mandatory in clinical research but remains optional in other research fields.
In this talk, we will address how preregistration could improve science and explain how early career researchers can benefit from it. We will introduce the different possibilities of preregistration and talk about their practicability in academia.

3. Replication by Ulf Toelch

There is a growing meta research literature indicating that a surprising number of study results are not reproducible. In this lecture, I will highlight causes of non-reproducible results. Specifically, I will discuss why non-reproducible results are actually to be expected. Drawing from psychology and biomedicine examples I will lay out when and how to replicate towards efficient and reliable research.

Thursday

1. Meta Research by Tracey Weissgerber

2. RRIDs for key resources: an easy way to improve reproducibility of manuscripts by Anita Bandrowski

Research Resource Identification, RRID, Initiative, a group dedicated to transforming scholarly communication, will be discussed as well as the SciScore tool, which helps to reduce the burden of authors trying to improve their papers.

3. Privacy-Preserving Data Sharing by Fabian Prasser and Thierry Meurers

Data sharing is considered an essential element of modern biomedical research. Unfortunately, despite its potential, data sharing is often associated with obstacles, particularly with regard to data protection. As a result, various approaches and infrastructures have been developed to ensure that patients and research participants remain anonymous when data is shared. However, protection of privacy usually comes at a cost, for example, in the form of limitations on the types of analyses that can be performed on shared data. In this lecture, we will present a systematization of privacy protection and the trade-offs that are made by different methods of data sharing. We will then categorize common approaches to data sharing and provide insights into gaps by analyzing combinations of promising properties and features not yet supported by existing approaches.

Friday

1. Why open science must be inclusive by Cassandra Gould van Praag

Discussion around why research may be more robust if it is inclusive, and consideration of the impact of poor inclusivity on the individual and field as a whole.

2. Open Publishing: finding open, visible, trusted venues to share your research findings by Jenny Delasalle

In the Guide for the European Commission’s Horizon Europe programme, scholars are advised to consider the right publishing venues and to implement open science practices. Open access (OA) to scientific publications is mandatory for grant beneficiaries. The European Commission is also one example of a research funder that has financed a publishing platform, so that authors can publish research outcomes in an open way at no cost to the authors. But what are publishing platforms and how do they differ from an OA journal? What about the green route to open access at no cost, where scholars deposit to a preprint server or an open access repository: are either of these the best venue for your work? The best open publishing venue or venues may depend on your research funder what exactly they mandate and support, on your institution’s financial support for OA and/or on other factors like the kind of audience you want to reach. Jenny Delasalle will present some useful tools to help you learn more about suitable options for open publishing of your scholarly outputs.

3. Transparency initiatives by Marike Schiffer & Student journal Berlin Exchange Medicine by Lara Weber and Raphael Leuner

Abstract of the workshops

Monday

Barcamps

Tuesday

1. Virtue Ethics: How to be a good researcher by Marlene Stoll

In research, we are sometimes faced with situations in which there is no crystal clear “right” or “wrong”, “good” or “bad”. Sometimes, we have to make difficult decisions. Although there are plenty of guidelines and codices, it is sometimes not easy to translate these rules into action. In the workshop, I will give a short introduction on the topic of research integrity and virtue ethics before we then talk about your experiences and do small exercises where you learn to reflect upon research integrity issues individually and as a group. There will also be time for exchange in small groups and for plenary discussions.

2. REDUCE: Determination of power and sample size for (animal) experiments by Lars Lewejohann

Calculating a sensible sample size is one of the most critical components of planning any research project. This is especially true for animal studies, where ethical aspects of animal welfare must be considered in addition to the pure scientific merit. The sample size must be chosen so that as few animals as possible are used, but at the same time the result should be statistically reliable. It must be emphasized here that too little numbers of animals may lead to overlooking biologically meaningful differences. In such a case, the animals, even if only a few, would have been used to no purpose. The calculation of the sample size depends on various factors. In this workshop, these factors will be evaluated and illustrated in hands on experiments and statistical exercises.

3. Intro to R by Anja Collazo and Meggie Danziger

Welcome to the R universe! In our interactive class room, we will get you started by familiarizing you with the open-source programming software R, the R-environment, data import/export and powerful packages for beginners. Through group-work you will learn first-and-easy steps on how to translate your goals for data wrangling, visualization and statistical analysis into R-language. Along the way, you will learn how to establish a reproducible workflow through R.

4. Systematic Review and Meta Analyses by Alexandra Bannach-Brown

Systematic review and meta-analysis are powerful tools to provide an unbiased overview of all available literature addressing a specific research question.
For more information on Preclinical Systematic Review and Meta-Analysis, please see http://camarades.de/

5. REPLACE: Standardisation and validation of test methods by Michael Oelgeschlaeger, Kostja Renko and Tanja Burgdorf & Lab Visit: Primary human lung tissue and organoids for replacement of animal research by Kantja Hoenzke

In vitro methods from basic science, reflecting “human” physiological processes, may also serve as assays to identify hazards and risks in toxicological testing. Thereby they gain additional translational value and might qualify as alternative or complementary methods to animal testing.
In this workshop we present the basic principles of standardisation and validation of new methods that allow regulatory acceptance of data for toxicological hazard identification or risk assessment. These principles are based on accepted OECD Guidance (Guidance Document on the Validation and International Acceptance of New or Updated Test Methods for Hazard Assessment) and Good in vitro Method Practise (GIVIMP) and ensure that a method is reliable (reproducible) and relevant for a given purpose.
This process is often refered to as time- and resource demanding, delaying the implementation of novel methods. We will discuss the reasons for delays in validation processes and also discuss novel approaches to validate and combine methods into testing strategies using the adverse-outcome pathway (AOP) concept
Using primary human material as well as organoids for ex vivo disease modeling efficiently supports translational research and fosters the mechanistic understanding of human lung disease. The course will give an overview of advantages, application areas and limitations of these two models. Practically human lung tissue explants and organoids will be phenotypically characterized by confocal and live cell imaging.

Wednesday

1. Data visualization: How to identify and fix common problems by Vladislav Nachev

Topics may include general techniques for making your figures accessible to a broad audience, learning to identify and fix common visualization errors in small sample size studies (bar graphs of continuous data, creating flow charts to track inclusion/exclusion, color blind accessible visualizations, using semi-transparency) and creating effective image-based figures (microscopy, electron microscopy, photographs, etc.). We will not address visualizations for big data, so attendees looking for this type of information might prefer to take another course.

2. Preregistration of animal studies by Julia Menon

This workshop focuses on the preregistration of animal study protocols and is divided into 3 parts.
Part 1 starts with a short introduction on the benefits of preregistration for animal studies, followed by the description and live demonstration of 3 platforms where preregistration can be done.
Part 2: after this theoretical part, participants will have an interactive discussion about preregistration, and notably about barriers and facilitators to animal studies preregistration.
Part 3: Participants will have a PC exercise where they can try to either register their own study or register an exercise protocol.

3. Preregistration: Why, What, Why Not, How by Malika Ihle

In this workshop I will give argue why creating a pre-analysis plan before conducting a study allows to prevent bias in empirical research. I will then give an overview of what preregistration and registered reports are, and review what detailed information they should contain. We will then collectively discuss benefits and disadvantages of embracing such practices, as well as possible fears and concerns. I will end by giving an overview of how to preregister in practice by giving a brief tutorial of the Open Science Framework preregistration plateform.

4. Publish my protocol workshop by Rene Bernard

Publications in methods journals reflect what one lab is doing at a single point in time. They can quickly become outdated, as most protocols continue to evolve after publication. Protocols.io is a protocol repository, which allows authors to deposit detailed protocols with additional features like pictures or short video clips, or timings for individual steps. The repository allows authors to create updated versions of their protocol at any time, so people who read your article can then go to protocols.io to find the latest version. This allows you to maintain a living protocol, which will make it easier for research within and outside your lab to follow your methods. Scientists outside your lab group can also “fork” your protocol by sharing their own modified version. New versions and forks link back to your original protocol, and protocols are citable with a DOI. This means that you get credit when others re-use your protocol.
During this workshop, participants will learn about depositing a protocol on protocols.io and what is needed to prepare a companion “Lab protocol” publication to submit to PLoS One. This new article type is designed to make research methods more transparent and reproducible by pairing a living protocol, deposited on protocols.io, with a brief Lab Protocol publication. This also allows authors to obtain credit for their methods development work by obtaining a peer-reviewed, published article. The method does not have to be a completely new invention but can be a variation or extension for a traditional or existing method that will benefit the research community.
Participants are encouraged to bring a research protocol they would like to publish or privately enter into protocols.io. We will try to group participants with similar methodologies.

Thursday

1. Reproducible Research in R: A Workshop on How to Do the Same Thing More Than Once by Aaron Peikert

Computational reproducibility is the ability to obtain identical results from the same data with the same computer code.
The high rate of irreproducible research limits the reach of results and decreases the efficiency of researchers.
Reproducible research is a building block for transparent and cumulative science because it enables the originator and other researchers, on other computers and later in time, to reproduce and thus understand how results came about.
Many researchers want their readers to get a deep understanding of their research and therefore want to work reproducibly, but it is not easy.
Considerable time is required to acquire the skills required for reproducible research, and the path is lined with pitfalls.
This workshop gets researchers up to speed on how to create reproducible data analyses in R (and beyond).
Specifically, researchers learn to automate the whole process from raw data to publishable manuscripts.
This automation is possible by combining dynamic document generation (via R Markdown), version control (via Git), workflow orchestration (via Make) and software management (via Docker).
These tools and, therefore, automatic reproduction of results are available on any machine with Docker installed.
The resulting workflow is, hence, highly transferable across machines and time.
These core properties of reproducibility are demonstrated for any reader by automatically reproducing the manuscript online.

2. REFINE by Kai Diederich

Scientific data from animals is questionable if the animals are not healthy and do not feel as comfortable as possible. In this workshop, we will discuss why the welfare of laboratory animals is critical to their suitability as model organisms for biological studies. We will explore how animal welfare can be objectively measured and what steps need to be taken to ensure optimal welfare during and outside of the experiment. We will discuss whether laboratory animals can become pathologically bored and how species-appropriate husbandry can prevent this. We will also introduce new approaches for analyzing animal behavior using deep learning techniques.

3. Science Communications - Why every researcher needs communication skills by Stefanie Seltmann and Katharina Kalhoff

You will hear about the daily work of a science communication office, learn why communicating is essential for every scientist and you will get some useful tipps and tricks on how to explain your research to a lay audience. And of course, you will acquire some practice by explaining your own research and will have lots of fun!

4. Version control with Git by Malika Ihle

In this facilitated self-paced tutorial, you will learn the basic concepts of version control. You will then practice version control using RStudio as one of many possible GUI interfaces that can interact with Git. You will learn how to use version control for your own workflow (Git within RStudio with backup online on GitHub) and for collaborative coding (fork, clone, pull requests on Github). The tutorials can be found at: https://malikaihle.github.io/Introduction-RStudio-Git-GitHub/ and https://malikaihle.github.io/Collaborative-RStudio-GitHub/. The targeted audience are complete novices regarding version control or Git, and who use RStudio at least occasionally.

Venue and rooms

Map of the CBF campus

Map of the CBF campus

Monday

Time Monday Location
9:00-10:00
10:00-11:00 Registration in front of room 5
11:00-12:00 Introduction to Barcamp Hörsaal/ lecture hall
——– ————- ——-
12:00-13:00 Break Break
——– ————- ——-
13:00-17:00 Barcamp Hörsaal/ lecture hall, room 5/6/10/ Blaue Grotte
18:00-21:00 Welcome Reception Trattoria Romana, Unter den Eichen 84, 12205 Berlin

Tuesday

Time Tuesday Location
9:00-10:00 Reproducibility Intro Hörsaal/ lecture hall
10:00-11:00 Research Ethics Hörsaal/ lecture hall
11:00-12:00 Waste and Value Hörsaal/ lecture hall
——– ————- ——-
12:00-13:00 Break Break
——– ————- ——-
13:00-17:00 1. Virtue Ethics Room ‘Blaue Grotte’- downstairs
13:00-17:00 2. REDUCE Room 10
13:00-17:00 3. Intro to R Room 5
13:00-17:00 4. Systematic Review Hörsaal/ lecture hall
13:00-17:00 5. REPLACE, Lab Visit Room 6 & Charité Campus Mitte, Charitéplatz 1/Virchowweg 9, 10117 Berlin

Wednesday

Time Monday Location
9:00-10:00 Research Data Management Hörsaal/ lecture hall
10:00-11:00 Preregistration Hörsaal/ lecture hall
11:00-12:00 Replication Hörsaal/ lecture hall
——– ————- ——-
12:00-13:00 Break Break
——– ————- ——-
13:00-17:00 1. Visualization Hörsaal/ lecture hall
13:00-17:00 2. Preregistration of Animal Studies Room 5
13:00-17:00 3. Preregistration Room 10
13:00-17:00 4. Publish your Protocol Room 6
18:00-19:00 Keynote Lecture Replication Tieranatomisches Theater, Philippstraße 13 (Campus Nord, Haus 3, 10115 Berlin)
19:00-21:30 Social event Tieranatomisches Theater

Thursday

Time Monday Location
9:00-10:00 Meta Research Hörsaal/ lecture hall
10:00-11:00 Screening Tools Hörsaal/ lecture hall
11:00-12:00 Privacy Preserving Data Sharing Hörsaal/ lecture hall
——– ————- ——-
12:00-13:00 Break Break
——– ————- ——-
13:00-17:00 1. Reproducible Analysis Hörsaal/ lecture hall
13:00-17:00 2. REFINE Room 6
13:00-17:00 3. Science Communication Room 5
13:00-17:00 4. GIT, GIT Hub Room 10
18:00-21:00 Speaker’s Dinner Restaurant Machiavelli, Albrechtstraße 13, 10117 Berlin

Friday

Time Monday Location
9:00-10:00 Diversity Hörsaal/ lecture hall
10:00-11:00 Open Publishing Hörsaal/ lecture hall
11:00-12:00 Transparency Initiative & Student Journal Berlin Exchange Medicine Hörsaal/ lecture hall
——– ————- ——-
12:00-13:00 Break Break
——– ————- ——-
13:00-17:00 Panel discussion Hörsaal/ lecture hall

Barcamp

Introduction to Barcamp

A Barcamp (or “unconference”) is an open meeting with open workshops that has no predefined program and no predefined speakers. Only the time schedule and the maximum number of topics are specified in advance. The content of Open and Responsible Research in the Life Sciences and the procedure are developed and self-organized by the participants. A Barcamp should enable all participants to present their own projects, ideas or questions in order to discuss these with other interested participants in so-called ‘sessions’. The main focus is on the exchange of experiences and ideas in order to promote different perspectives.

Course of the Barcamp at the Summer School

First we will explain the Barcamp framework, as well as the topic selection and the schedule development. We will have time for a total of 15 possible topics, of which 3 or more sessions can be attended.
Then you will get the time to suggest and briefly describe your topics of interest that you would like to discuss in the upcoming Barcamp hours. Thereafter, the group develops a session schedule by writing the suggested topics on a whiteboard or by using Post-it notes, considering the prespecified time. Timeslots can be occupied multiple times by different topics if there are more topics than timeslots. You (as a group) can decide whether to group similar topics into one session. Once all timeslots are filled, you can write your name under the topics you are interested in. By this, you directly decide which session you would like to attend. Without interested participants a session will not take place. Within a session, each participant is a speaker and responsible for an interactive and friendly discussion. One protocolist volunteers.

Goal

The goal of a Barcamp is to provide a lively platform for participants to connect, network, exchange ideas and engage in discussions. It depends on the dynamics of the participants. It’s possible to increase level of knowledge through information exchange, to develop new (project) ideas or concrete results. These concrete results can arise if, for example, questions from the participants are answered.
A friendly, respectfully and tolerant atmosphere is expected and contributes to the success of a Barcamp.

Rules of a Barcamp:

1. What is discussed is determined by you.
2. One question can be sufficient input to start a session
3. Present your topic briefly and concisely.
4. There can be as many sessions as there are rooms.
5. A session can take place if it interests at least two people.
6. One person can offer more than one session.
7. Each session is documented.
8. It is okay to leave a session in the middle. (if you can’t contribute to the session or you don’t benefit from attending)
9. A session lasts no longer than 45 minutes.
In case you don’t have enough time for a good conversation or networking during the Barcamp, you will have the opportunity to continue at the following Welcome Reception over some drinks and snacks.